Cannabidiol —CBD— is a compound in Cannabis that offers various beneficial properties. Taken alone, CBD is not psychoactive; when mixed with THC it tends to smooth and modulate the euphoric effects of THC, often this is something patients tend to dislike in high THC strains.
After decades only high-THC Cannabis, CBD-rich strains are now being grown by and for medical patients. CBD has demonstrated neuro-protective effects in some pathological conditions, and its anti-cancer potential is currently being explored at several academic research centers worldwide.
CBD is one of over 60+ compounds found in cannabis that belong to a class of molecules called cannabinoids. Of these compounds, CBD and THC are usually present in the highest concentrations, and are therefore the most recognized and studied.
All our genetics will have traces of all canabinoids found naturally in the plants genetics, as we believe in the entourage effect of the plant to be the most effective for most patients.
CBD and THC levels tend to vary between different strains and varieties of cannabis. By using selective breeding techniques, we have managed to create varieties with high levels of CBD and THC.
CBD does not cause a high, unlike THC. The reason why CBD is non-psychoactive is due to its lack of affinity for CB1 receptors. CB1 receptors are found in high concentrations in the brain, and are the pathways responsible for the psychoactive effects of THC.
Numerous studies suggest CBD acts to counter the intoxicating effects of THC, including memory impairment and paranoia. But cannabis with both CBD & THC is still psychoactive, just at a different level.
Both CBD and THC have been found to present no risk of lethal overdose. However, to reduce potential side effects, medical users may be better off using cannabis strains with higher levels of CBD.
New data indicates that CBD interacts directly with the CB1 receptor site in ways that are therapeutically relevant. CBD parks at a different docking site on the CB1 that is functionally distinct from THC’s orthosteric binding site. When docked, it influences how the receptor responds to stimulation by THC and the endogenous cannabinoids. This can have a dramatic impact on the efficiency of cell signaling.
CBD could be effective in easing symptoms of a wide range of difficult-to-control conditions, including:
Rheumatoid arthritis, Diabetes, Alcoholism, PTSD, epilepsy, antibiotic-resistant infections and neurological disorders.